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Introduction to Infection Prevention

Course Number: 582

Susceptible Host

Infection is the result of complex interactions between host and pathogenic organisms. While the numbers, pathogenicity, virulence, and antigenicity of organisms are important determinants; the establishment of infection and its severity relate to the state of host defense mechanisms.1 Some susceptible hosts become colonized but remain asymptomatic. Others progress from colonization to symptomatic disease, either immediately or following a period of asymptomatic latency.