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Cardiovascular Drugs Our Patients Take

Course Number: 581

Key Points for Practice

In 2020, there were 52 single cardiovascular agents and 8 combination agents (see Table 6) that were in the top 300 prescription drugs dispensed by U.S. community pharmacies.2 Predicated on the mechanisms of action of these drugs, the most common cardiovascular conditions encountered in ambulatory settings include hypertension (HTN); ischemic heart disease (IHD), i.e., chronic coronary artery disease (CAD) and acute coronary syndromes (ACS); cardiac arrhythmias; heart failure (HF); and thromboembolic complications.2-10,17

Table 6. Combination Cardiovascular Drugs.2,9,10

Combinations (Rank/300)Common Indications
Hydrochlorothiazide / Lisinopril (50)• Hypertension
Losartan / Hydrochlorothiazide (93)• Hypertension
• Hypertension with heart left ventricular hypertrophy
Hydrochlorothiazide / Triamterene (131)• Hypokalemia associated the hydrochlorothiazide use
Amlodipine / Benazepril (169)• Hypertension
Sacubitril / Valsartan (219)• Heart failure
Hydrochlorothiazide / Valsartan (235)• Hypertension
Hydrochlorothiazide / Olmesartan (281)• Hypertension
Bisoprolol / Hydrochlorothiazide (290)• Hypertension