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Postexposure Evaluation and Follow-up

Course Number: 472

Healthcare-associated Exposure to the Hepatitis A Virus (HAV)

HAV is transmitted primarily by the fecal-oral route, either person-to-person, i.e., close personal contact with an infected household member or sex partner; or consumption of contaminated food or water.24 HCP have not been demonstrated to be at increased risk for HAV infection because of occupational exposure.24

However, HCP traveling to or working in countries that have high or intermediate hepatitis A endemicity should complete a 2 dose HepA vaccination regimen (Havrix or Vaqta) prior to travel. Unprotected HCP exposed to HAV should be administered PEP consisting of the HepA vaccine within 2 weeks of exposure and, under certain circumstances, coadministration of immune globulin (GamaSTAN IG) for HCP >40 years of age.24